Collaboration Agreements and Supply Agreements - Additional Information (Details)
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1 Months Ended |
3 Months Ended |
9 Months Ended |
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Oct. 01, 2018
USD ($)
$ / shares
shares
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Sep. 30, 2018
USD ($)
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Aug. 31, 2018
USD ($)
Program
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Jul. 31, 2018
Program
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Aug. 31, 2017
USD ($)
Program
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Jun. 30, 2016
USD ($)
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Mar. 31, 2015
USD ($)
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Sep. 30, 2014
USD ($)
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May 31, 2014
USD ($)
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Sep. 30, 2018
USD ($)
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Jul. 31, 2018
USD ($)
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Sep. 30, 2018
USD ($)
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Sep. 30, 2017
USD ($)
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Dec. 31, 2017
USD ($)
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Accounts receivable, related parties |
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$ 1,695,000
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$ 1,695,000
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$ 1,695,000
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$ 784,000
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Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs |
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84,739,000
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$ 0
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Accounts receivable |
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2,443,000
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2,443,000
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2,443,000
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1,624,000
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Series E Redeemable Convertible Preferred Stock |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs |
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$ 85,400,000
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Subsequent Event | Common Stock | IPO |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Issuance of common stock, shares | shares |
5,667,000
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Share issue price per share | $ / shares |
$ 15.00
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SutroVax |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Accounts receivable |
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584,000
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584,000
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584,000
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34,000
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2014 Celgene Agreement | Celgene |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Up-front, nonrefundable payment received |
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$ 83,100,000
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Revenue recognized from payments ratably over period |
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3 years
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Contingent payment received |
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$ 15,000,000
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Milestone payment received |
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$ 25,000,000
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Deferred revenue |
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$ 8,200,000
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2017 Celgene Agreement | Celgene |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Revenue recognized from payments ratably over period |
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3 years
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Number of programs advancing through preclinical development | Program |
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4
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Option fee payment received |
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$ 12,500,000
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Second option fee payment received |
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$ 12,500,000
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Number of investigational new drug program | Program |
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1
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Recognized of deferred revenue over the entire period |
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$ 12,500,000
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Milestone revenue recognized |
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10,000,000
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Deferred revenue |
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13,100,000
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13,100,000
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13,100,000
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18,000,000
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Potential milestone future payment received of manufacturing activities |
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10,000,000
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10,000,000
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10,000,000
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Accounts receivable, related parties |
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$ 300,000
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300,000
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300,000
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800,000
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2017 Celgene Agreement | Celgene | Licensed Products |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Maximum aggregate milestone and option fee payments eligible to receive |
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295,000,000
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2017 Celgene Agreement | Celgene | Other Licensed Products |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Maximum aggregate milestone and option fee payments eligible to receive |
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393,700,000
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2018 Master Services Agreement |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Revenue from other related parties |
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$ 300,000
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$ 3,900,000
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2018 Merck Agreement | Merck Sharp & Dohme Corp |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Revenue recognized from payments ratably over period |
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4 years
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4 years
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4 years
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Deferred revenue |
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$ 57,200,000
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$ 57,200,000
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$ 57,200,000
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Number of research programs | Program |
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3
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Upfront payment received |
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$ 60,000,000
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Number of target programs | Program |
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2
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Starting term of recognizing revenues from up front payment |
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2018-07
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Revenue recognition aggregate milestone payments eligible to receive |
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$ 1,600,000,000
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Revenue recognition milestone method description |
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If one or more products from each of the target programs are developed for non-oncology or a single indication, the Company will be eligible for reduced aggregate milestone payments. In addition, the Company is eligible to receive tiered royalties ranging from mid-single digit to low teen percentages on the worldwide sales of any commercial products that may result from the collaboration.
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Accounts receivable |
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$ 800,000
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$ 800,000
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$ 800,000
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2018 Merck Agreement | Merck Sharp & Dohme Corp | Subsequent Event | Common Stock | IPO |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Issuance of common stock, shares | shares |
666,666
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Share issue price per share | $ / shares |
$ 15.00
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Proceeds from issuance of common stock |
$ 10,000,000
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2018 Merck Agreement | Merck Sharp & Dohme Corp | Subsequent Event | Series E Redeemable Convertible Preferred Stock |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Issuance of common stock, shares | shares |
74,794,315
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Share issue price per share | $ / shares |
$ 0.2674
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Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs |
$ 20,000,000
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Collaboration Agreement | EMD Serono |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Up-front, nonrefundable and non-creditable payment received |
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$ 10,000,000
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MDA Agreement | EMD Serono |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Revenue recognized from payments ratably over period |
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5 years
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5 years
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5 years
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Deferred revenue |
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$ 2,800,000
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$ 2,800,000
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$ 2,800,000
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5,900,000
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Starting term of recognizing revenues from up front payment |
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2014-06
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Up-front, nonrefundable and non-creditable payment received |
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$ 10,000,000
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Maximum amount eligible to receive for each product developed |
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$ 52,500,000
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Accounts receivable |
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700,000
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700,000
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700,000
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$ 800,000
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Supply Agreement | SutroVax |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Accounts receivable, related parties |
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$ 600,000
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600,000
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600,000
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Other revenue-related parties |
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$ 600,000
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$ 1,500,000
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Research Development and Commercialization Agreement | The Leukemia & Lymphoma Society, Inc. |
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |
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Maximum contribution in clinical development |
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6,000,000
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Initial milestone payment |
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500,000
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Total milestone payments received |
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$ 1,000,000
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Research development and commercialization agreement termination period |
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12 years
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Research development and commercialization agreement termination description |
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The LLS Agreement terminates upon the earlier of (a) fulfillment of all payment obligations by both parties or (b) 12 years after the effective date. LLS may terminate the LLS Agreement at any time with 60 days’ prior written notice. Either the Company or LLS has the right to terminate the LLS Agreement based on the other party’s uncured material breach.
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Other liabilities related to payments received |
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$ 1,000,000
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