Quarterly report pursuant to Section 13 or 15(d)

Equity Incentive Plans, Employee Stock Purchase Plan and Stock-Based Compensation (Tables)

v3.22.2.2
Equity Incentive Plans, Employee Stock Purchase Plan and Stock-Based Compensation (Tables)
 9 Months Ended
Sep. 30, 2022
Share-Based Payment Arrangement [Abstract]  
Summary of Option Activity

The following table summarizes option activity under the Company’s 2004 Plan, 2018 Plan and 2021 Plan:

 

 

 

Shares

 

 

Weighted-
Average
Exercise Price

 

Stock options outstanding at December 31, 2021

 

 

6,512,086

 

 

$

13.86

 

Granted

 

 

1,352,500

 

 

 

7.16

 

Exercised

 

 

(49,454

)

 

 

5.39

 

Canceled and forfeited

 

 

(341,605

)

 

 

14.22

 

Stock options outstanding at September 30, 2022

 

 

7,473,527

 

 

 

12.69

 

Stock options exercisable at September 30, 2022

 

 

4,960,812

 

 

$

13.13

 

 
Summary of Status and Activity of Non-vested RSUs

A summary of the status and activity of non-vested RSUs during the nine months ended September 30, 2022 is as follows:

 

 

 

Number of
shares

 

 

Weighted
Average
Grant-Date
Fair Value

 

Non-vested December 31, 2021

 

 

2,403,826

 

 

$

18.43

 

Granted

 

 

2,407,000

 

 

 

7.70

 

Vested and released

 

 

(573,981

)

 

 

17.84

 

Canceled and forfeited

 

 

(343,775

)

 

 

14.89

 

Non-vested September 30, 2022

 

 

3,893,070

 

 

$

12.19

 
Schedule of Stock-Based Compensation Expense Recognized

Total stock-based compensation expense recognized was as follows:

 

 

 

Three Months Ended

 

 

Nine Months Ended

 

 

 

September 30,

 

 

September 30,

 

 

 

2022

 

 

2021

 

 

2022

 

 

2021

 

 

 

(in thousands)

 

 

(in thousands)

 

Research and development expense:

 

$

2,630

 

 

$

1,933

 

 

$

7,514

 

 

$

4,882

 

General and administrative expense:

 

 

4,152

 

 

 

4,562

 

 

 

12,938

 

 

 

11,472

 

Total

 

$

6,782

 

 

$

6,495

 

 

$

20,452

 

 

$

16,354