Functional Leadership Team

Kwadwo Bediako joins Sutro BioPharma from Seagen Inc. where he was an Executive Director, Global Product Team Lead (PTL) within the Program and Portfolio Management group. While at Seagen, Mr. Bediako provided global program strategic leadership and execution for two key commercial products: ADCETRIS® and TIVDAK® within the oncology therapeutic area. As a PTL, ADCETRIS® submitted and received Seagen’s first pediatric approval in Classic Hodgkin lymphoma (cHL) among other notable global label expansion submissions for the product.

Prior to Seagen, Kwadwo worked at global companies, including Orchard Therapeutics, Gilead, Amgen and MedImmune (now AstraZeneca), where he had increasing leadership responsibilities within the program management and leadership across multiple oncology programs in early and stage development with a successful track record.

Mr. Bediako received his B.S from D’Youville University and M.S and MBA from Johns Hopkins University

Craig Berman, M.D. has over 17 years of experience in drug development and held increasing leadership positions. Most recently, as a Vice President of Clinical Development at QED Therapeutics. Dr. Berman lead the clinical development of PEGPH20 at Halozyme from 2016-2018, cabozantinib at Exelixis 2013-2015, and enzalutamide at Medivation (currently Pfizer) 2009-2013, including successful NDA and launch. Dr. Berman has worked on several immune oncology programs including, GVAX whole cell vaccine at Cell Genesys, intratumoral injection of TLR-9 agonists in combination with pembrolizumab at Dynavax, and PEGPH20 in combination with atezolizumab in collaboration with Genentech and Halozyme. Dr. Berman received a B.A. in Chemistry from Northwestern University in Evanston, an M.D. from the University of Colorado Health Sciences Center and completed a residency in urology at the University of Iowa and post-residency training in urologic oncology at the University of Colorado.

Dr. Garrison Beye is an experienced biotech leader with over 20 years of industrial experience covering research through commercial pharmaceutical production. Over his career, Dr. Beye has contributed to the development, commercialization, and/or commercial production of a multitude of approved drug products, including: Photofrin®, Visudyne®, Avonex®, Tysabri®, Amevive®, Zynrelef®, Kogenate®, Kovaltry®, and Jivi®. Most recently, Dr. Beye led the multi-product, vial-to-vial Quality Control function at the Bayer Supply Center in Berkeley California that distributed recombinant rFVIII to patients world wide. Dr. Beye is the author of multiple journal articles, a book chapter, and shares invention of a patent. Dr. Beye holds a Ph.D. (organic chemistry) and an MBA.

Dr. Bleker joins Sutro Biopharma with over 18 years of experience in drug development including pre- and post-market pharmacovigilance, as well as medical affairs. He received a B.S. in psychobiology from the University of California, Riverside, and M.D. from Xochicalco University in Baja California, Mexico. Prior to joining Sutro, Dr. Bleker served as head of pharmacovigilance and safety risk management at Mirati Therapeutics. At Mirati, he established the pharmacovigilance department and supported the entire Mirati portfolio including the development of their KRASG12C Inhibitor, KrazatiTM (adagrasib), from first-in-human study through FDA approval. Prior leadership roles include head of drug safety at Nektar Therapeutics, Santarus where Dr. Bleker contributed to FDA approval of Uceris® (budesonide), and Hana Biosciences.

Regina Cheng has over 25 years of financial accounting experience and has managed our finance and accounting team since 2015. Prior to joining Sutro, while at Keynote Systems (acquired by Thoma Bravo, LLC), she built and led the finance team as the company’s first controller and assisted in its highly successful initial public offering and follow-on financing. Ms. Cheng has also held various corporate and divisional controllership management positions at several private and publicly held technology companies, such as CompareNetworks, Inc., TeraRecon (acquired by SymphonyAI Group), Sungard Data Systems (acquired by FIS) and Sterling Software (acquired by Computer Associates). Ms. Cheng received her B.A. from the University of California, Berkeley, and is a certified public accountant (inactive status) in California.

Mark Fisher joins Sutro Biopharma with over 25 years of clinical operations experience, specializing in oncology-focused investigational programs across all phases of clinical development. He has been responsible for developing successful global clinical operations strategies, building high-performing clinical operations teams, and, most recently, serving as the Head of Hematology/Oncology Clinical Operations at AstraZeneca, where he also acted as the West Coast site head.

Mark has held senior leadership positions at Acerta Pharma, Gilead, and Roche/Genentech. He brings extensive experience in global regulatory inspections and audits, with a strong focus on ensuring inspection readiness for global registrational filings. His primary therapeutic areas of expertise include oncology, hematology/oncology, immuno-oncology (IO), and cell therapy. Mark has been instrumental in securing successful regulatory filings for several marketed products, including Rituxan/MabThera, Xeloda, Venclexta, Calquence, Polatuzimab, Gazya, and Avastin. Mark is also a retired, service-decorated U.S. Navy veteran and holds a B.S. in Molecular Biology/Biochemistry from San Francisco State University.

Dr. Heidi Hoffmann, VP Supply Chain, has 27+ years of experience in biotechnology, specializing in process development, technology transfer, manufacturing of vaccines and biological therapeutics. After receiving her Ph.D. from the University of California, Berkeley, Heidi began her career at Aviron, where she worked on process development and production of vaccines for EBV, PIV and influenza (FluMist®). Heidi then joined Valentis, where she led the team responsible for process development, technology transfer and clinical production of plasmid DNA for gene therapy. In 2002, Heidi returned to vaccine work by joining VaxGen, Dr. Hoffmann was responsible for process development and manufacturing of anthrax vaccine. Later, Heidi transitioned into a technology transfer role, hiring and leading the VaxGen oversight team for the successful transfer of commercial production of Bristol-Meyer Squibb’s Orencia® (abatacept) into the Celltrion manufacturing facility in South Korea. After completion, Heidi joined non-profit Global Solutions for Infectious Diseases (GSID) as Project Director responsible for coordinating the outsourcing of process development and manufacture of HIV vaccines. Dr. Hoffmann joined Sutro in February 2011, and currently leads Supply Chain as well as outsourced cGMP manufacturing for protein therapeutics and ADCs produced using Sutro’s proprietary cell-free protein expression system.

Carlos Lugo has over 30 years of combined experience in Quality, Compliance, Regulatory Affairs, Validation and Manufacturing, and has been the Head of Quality for Sutro since 2016. Prior to joining Sutro, Carlos held the role of Global Quality Systems Director at Bayer supporting Kogenate™ and Kovaltry™ hematology products. Similarly, as QA Director, he was directly involved in the early phase clinical supply activities leading to the successful commercial launch of Keytruda® at Merck & Co. Carlos has also held various increased leadership positions at Hospira (acquired by Pfizer), Johnson & Johnson, Bristol-Myers Squibb and Baxter supporting large molecules, small molecules, medical devices and combination products. Mr. Lugo received his B.S. in Chemical Engineering from the University of Puerto Rico, Mayagüez Campus.

Mr. Luhar has over 30 years of experience in biotech operations, including Manufacturing, Manufacturing Science and Technology, Engineering and Logistics. He joined Sutro in 2016 as Senior Director of Manufacturing and was promoted to Executive Director in 2018. At Sutro, Mr. Luhar has led the formation of Sutro’s manufacturing organization and GMP compliant operations and is responsible for Sutro’s cGMP manufacturing facility. Prior to joining Sutro, Mr. Luhar held senior leadership positions at Boehringer-Ingelheim, Novartis, Genzyme, and Baxter Bioscience where he worked for 18 years. Mr. Luhar received his B.A. in Biology from San Jose State University.

Steve Michel, M.B.A., VP Information Technology & Facilities Operations, joined Sutro as a consultant in 2009 and has 30 years of operations experience. Early in his career, he worked in digital photography at Sony Corporation, followed by managing life sciences IT for Arris Pharmaceuticals, AXYS Advanced Technologies and Discovery Partners International.

Previously, led the sales team at Apple, North America as their Retail Business Development Manager. Afterwards, joined Workwerks as their Transportation Commerce Software Developer and created IT consultancy Strategic Entrance, LLC.

While at Sutro, he leads IT and R&D facilities operations as well as construction management, EH&S, procurement and software development for scientific & business needs. Steve earned his M.B.A. from University of Illinois, B.F.A. from University of Southern California and maintains current PMP & PMI-ACP certifications.

Werner Rubas, Ph.D., brings to Sutro 30 years of biotech and pharmaceutical industry experience. Formerly, Dr. Rubas was at Nektar Therapeutics for over nine years, most recently as Executive Director in Non-Clinical Pharmacokinetics and Pharmacodynamics. At Nektar he provided leadership support, directed the generation of data packages for regulatory submissions of NKTR-214, NKTR-358, NKTR-262 and NKTR-255, filed a patent application for an immunotherapeutic tumor treatment method, and provided scientific input on cross-functional teams from research concepts to late stage development. Prior to Nektar, Dr. Werner was at Roche in Palo Alto, where he was the Associate Director of the Drug Metabolism and Pharmacokinetics group. Additionally, he has been a SPARK advisor at Stanford University since 2010 and lectures classes on Drug Development at UC Berkeley Extension. Dr. Rubas earned his Ph.D. from ETH, Zurich and received his pharmacy license from the School of Pharmacy at ETH, Zurich.

Dr. Sethi has over 30 years of experience across all stages of drug development, from preclinical studies to post-approval lifecycle management. Her career includes roles at large pharmaceutical companies such as Johnson & Johnson, AstraZeneca, and Roche, as well as at smaller and midsize firms including Chemocentryx, Elan Pharmaceuticals, Everest BioPharma Group, and Sarah Cannon. Dr. Sethi has played a pivotal role in the approval and commercialization of over 21 novel drugs, biologics, and device combinations while building and leading high-performing teams. Most recently, she has led the development of two orphan gene therapy programs in the US and Europe, managing regulatory affairs, medical writing, and pharmacovigilance functions. She currently serves on the Board of Directors for three organizations. Dr. Sethi holds a Doctorate and a B.S. in Pharmacy and is a registered pharmacist in California and New Jersey.

Kris Treanor brings 20 years of combined experience in the healthcare industry. She began her career at ZS Associates, a global consulting firm, where she spent 6 years solving a variety of complex business problems, all with the underlying goal of advancing healthcare. Since then, Kris has held roles of increasing scope and responsibilities at a number of biopharma companies, providing insights and contributing to key strategic decisions.

Prior to joining Sutro in 2022, she spent over 3 years at BeiGene, where she was integral in planning the commercial strategy and launch success of zanubrutinib in Mantle Cell Lymphoma and subsequent indications. At Sutro, Kris leads commercial strategy and new product planning.

She received her Sc. B. in Biology at Brown University and her M.S. in Microbiology & Immunology at Stanford University.

Ganesh Vissvesvaran joined Sutro in 2019 with extensive experience in technical leadership roles at the site and global level in process development, global manufacturing, engineering and technical services. Throughout his career, he has demonstrated a strong passion for innovation and efficiency in delivering life-savings drugs to patients.

Prior to joining Sutro, Mr. Ganesh held various roles of increasing responsibility at Genentech in Process Technology Development and Global MSAT. Prior to his tenure at Genentech, Mr. Ganesh held development leadership roles at Baxter BioScience and Trubion Pharmaceuticals. In these roles, He contributed to global manufacturing license expansion for RITUXAN®, ACTIVASE® and ADVATE®. He has authored and contributed to a few patents in the areas of technology, engineering and process science.

Mr. Ganesh received a Bachelor of Engineering (Hons.) degree from Birla Institute of Technology and Science, (B.I.T.S), Pilani, India and a Master of Science degree from Oregon State University, both in Chemical Engineering.

Dr. Alice Yam is an experienced leader with 20 years of experience in research and biologics drug discovery. As Vice President of Drug Discovery at Sutro Biopharma, she has a proven track record of successfully building preclinical portfolios, contributing to the identification and optimization of several clinical assets. In particular, she was responsible for the discovery program for M1231, a novel MUC1-EGFR bispecific ADC developed in partnership with EMD Serono. Her work has focused in several areas including antibody discovery, protein engineering, and preclinical development.

Prior to Sutro, Alice worked in biomarker development at Novartis Vaccines & Diagnostics where she focused on aggregation-mediated diseases like Alzheimer’s Disease and Parkinson’s Disease. Subsequently, she joined Sutro in 2012 to work on drug development where she took on responsibilities in both functional and program leadership. Alice earned her Ph.D. in Biological Sciences from Stanford University and her B.S. in Bioengineering from the University of California, Berkeley.

Dr. Gang Yin is an accomplished scientist and experienced R&D team leader with over 18 years of expertise in research and drug development. After earning his Ph.D. from Tsinghua University, he started working on the development and application of Cell-free protein synthesis in the lab of Prof. Jim Swartz at Stanford University. In 2004, Dr. Yin joined Sutro Biopharma where he has held various positions and is currently leading the Platform Engineering and Process Research Department.

With a proven track record of success as a project leader on multiple programs, Dr. Yin has contributed to the progression of several programs into clinical trials. Notably, the collaboration with Merck led to the discovery of MK-1484. Dr. Yin is an expert in ADC and cytokine biologics development strategies, with a particular emphasis on strain engineering, antibody discovery, expression, purification, conjugation, and drug lead characterization. He is the pioneer of site-specific ADC development through non-natural amino acid incorporation.

Dr. Yin's strategic and scientific leadership skills, coupled with his expertise in protein biochemistry, have significantly contributed to the success of the company. He has authored 30+ publications and holds 10+ patents.