Annual report pursuant to Section 13 and 15(d)

Commitments and Contingencies - Additional Information (Details)

v3.22.0.1
Commitments and Contingencies - Additional Information (Details)
$ in Thousands
 1 Months Ended 12 Months Ended
Jun. 30, 2021
USD ($)
Sep. 30, 2020
USD ($)
ft²
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Jul. 31, 2021
ft²
Loss Contingencies [Line Items]            
Aggregate estimated base rent payments due     $ 45,694      
Deferred rent       $ 1,340    
Rent expense       4,700 $ 3,600  
Operating lease expense     8,400      
Operating lease payments     $ 6,200      
Operating lease, weighted average remaining lease term     5 years 8 months 12 days      
Operating lease, weighted average discount rate, percent     10.80%      
Sublease Agreement            
Loss Contingencies [Line Items]            
Security deposit     $ 900 $ 900    
Sublease Agreement | Five Prime Therapeutics, Inc. (the “Sublessor”)            
Loss Contingencies [Line Items]            
Area of Sublease Premises | ft²   115,466        
Lease expiration Date   Dec. 31, 2027        
Aggregate estimated base rent payments due   $ 39,100        
Lease base rent abatement   $ 5,200        
San Carlos Lease | California            
Loss Contingencies [Line Items]            
Lease extension period 5 years          
Lease expiration Date Jul. 31, 2026          
Lease renewal term 5 years          
Aggregate estimated base rent payments due $ 4,200          
Industrial Lease | California            
Loss Contingencies [Line Items]            
Lease extension period 5 years          
Lease expiration Date Jun. 30, 2026          
Lease renewal term 5 years          
Aggregate estimated base rent payments due $ 4,300          
Initial Premises | Sublease Agreement | Five Prime Therapeutics, Inc. (the “Sublessor”)            
Loss Contingencies [Line Items]            
Area of Sublease Premises | ft²           85,755
Expansion Premises | Sublease Agreement | Five Prime Therapeutics, Inc. (the “Sublessor”)            
Loss Contingencies [Line Items]            
Area of Sublease Premises | ft²   29,711