Quarterly report pursuant to Section 13 or 15(d)

Collaboration and License Agreements and Supply Agreements - Additional Information (Details)

v3.20.2
Collaboration and License Agreements and Supply Agreements - Additional Information (Details)
1 Months Ended 3 Months Ended 9 Months Ended
Apr. 30, 2020
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Mar. 31, 2020
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Feb. 29, 2020
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May 31, 2019
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Dec. 31, 2018
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Aug. 31, 2018
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Program
Jul. 31, 2018
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Sep. 30, 2017
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Aug. 31, 2017
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Program
Jun. 30, 2016
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Mar. 31, 2015
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Sep. 30, 2014
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May 31, 2014
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Sep. 30, 2020
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Mar. 31, 2020
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Sep. 30, 2019
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Sep. 30, 2020
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Sep. 30, 2019
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Dec. 31, 2019
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Jan. 01, 2019
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Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Contingent payments of embedded derivative and related liability                           $ 200,000     $ 200,000   $ 100,000  
EMD Serono                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Recognition of up front payment                           20,000,000.0     20,000,000.0      
Changes in deferred revenue                                 $ 600,000      
The Leukemia & Lymphoma Society, Inc.                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Research development and commercialization agreement termination period                                 12 years      
Research development and commercialization agreement termination description                                 The LLS Agreement terminates upon the earlier of (a) fulfillment of all payment obligations by both parties or (b) 12 years after the effective date.  LLS may terminate the LLS Agreement at any time with 60 days’ prior written notice. Either the Company or LLS has the right to terminate the LLS Agreement based on the other party’s uncured material breach.      
First Cytokine-Derivative Program | Merck Sharp & Dohme Corp                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Extended research term   1 year                                    
Upfront payment received   $ 5,000,000.0                                    
Revenue, remaining performance obligation, amount   0                         $ 0          
Recognition of up front payment   50,500,000                         50,500,000          
Transaction price   65,000,000.0 $ 60,000,000.0                                  
Constrained variable consideration     $ 5,000,000.0                                  
Revenue reallocated property rights   7,800,000                                    
Incremental revenue recognized reallocated target programs   $ 500,000                                    
Estimated service period   3 years                                    
Incremental revenue recognized   $ 1,500,000                                    
Adjustments to transaction price   5,900,000                                    
Cumulative catch-up in revenue                             2,000,000.0          
Development and Manufacturing Services | Vaxcyte, Inc.                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Upfront payment received $ 200,000                                      
Celgene Agreement                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Upfront, nonrefundable payment received                       $ 83,100,000                
Contingent payment received                     $ 15,000,000.0                  
Milestone payment received                   $ 25,000,000.0                    
Additional milestone payment received                   $ 10,000,000.0                    
Option fee payment received                 $ 12,500,000                      
Milestone revenue recognized         $ 10,000,000.0     $ 10,000,000.0                        
Contingent payments       $ 275,000,000.0                                
Option maintenance fee                 $ 12,500,000                      
Number of programs advancing through preclinical development | Program                 4                      
Deferred revenue                 $ 8,200,000         0     $ 0   3,000,000.0  
Revenue, remaining performance obligation, amount                 20,700,000                      
Celgene Agreement | ASC 606 | Difference between Revenue Guidance in Effect before and after Topic 606                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Deferred revenue                                       $ (4,500,000)
Celgene Agreement | First Performance Obligation                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Revenue, remaining performance obligation, amount                 8,200,000                      
Celgene Agreement | Future Services on Collaboration Joint Steering Committee ("JSC")                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Revenue, remaining performance obligation, amount                 200,000                      
Celgene Agreement | Third Performance Obligation                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Revenue, remaining performance obligation, amount                 $ 12,300,000                      
Partially Unsatisfied Performance Obligations                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Total revenue                           1,000,000.0   $ 1,000,000.0 3,000,000.0 $ 2,900,000    
Partially Unsatisfied Performance Obligations | EMD Serono                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Total revenue                               1,500,000   3,800,000    
Research and Development Services                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Total revenue                           200,000   100,000 600,000 400,000    
Research and Development Services | EMD Serono                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Total revenue                           300,000   500,000 1,100,000 2,200,000    
2018 Celgene Master Services Agreement                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Other revenue-related parties                           5,900,000   2,200,000 7,100,000 3,200,000    
2018 Merck Agreement                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Upfront payment received           $ 60,000,000.0                            
Deferred revenue                           23,900,000     23,900,000   31,900,000  
Number of research programs | Program           2                            
Revenue recognized performance obligation                             47,100,000          
Transaction price                             $ 60,000,000.0          
2018 Merck Agreement | ASC 606 | Celgene Corporation                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Changes in deferred revenue due to adoption of new accounting policy                                       $ 6,300,000
2018 Merck Agreement | Merck Sharp & Dohme Corp                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Upfront payment received           $ 60,000,000.0                     60,000,000.0      
Number of research programs | Program             3                          
Revenue from first performance obligation           7,300,000                            
Recognition of up front payment           47,100,000                            
Revenue recognized performance obligation           700,000                            
Extension option fee associated with contingent program           4,900,000                            
Increase (decrease) in revenue   (5,100,000)                                    
Embedded interest associated with upfront payment                           400,000   800,000 1,500,000 2,500,000    
FTE Funding Received                           1,700,000   900,000 4,200,000 2,600,000    
Revenue recognition aggregate milestone payments eligible to receive                                 $ 1,600,000,000      
Milestone method revenue recognition description                                 If one or more products from each of the target programs are developed for non-oncology or a single indication, the Company will be eligible for reduced aggregate milestone payments. In addition, the Company is eligible to receive tiered royalties ranging from mid-single digit to low teen percentages on the worldwide sales of any commercial products that may result from the collaboration.      
2018 Merck Agreement | Merck Sharp & Dohme Corp | First Target Program                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Increase (decrease) in revenue   (6,200,000)                                    
2018 Merck Agreement | Merck Sharp & Dohme Corp | Second Target Program                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Increase (decrease) in revenue   $ 1,100,000                                    
2018 Merck Agreement | Merck Sharp & Dohme Corp | Partially Unsatisfied Performance Obligations                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Total revenue                           6,900,000   3,800,000 $ 13,000,000.0 10,500,000    
2018 Merck Agreement | Merck Sharp & Dohme Corp | ASC 606                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Total interest of unearned revenue                           7,300,000     7,300,000      
Collaboration Agreement | EMD Serono                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Up-front, nonrefundable and non-creditable payment received                         $ 10,000,000.0              
MDA Agreement | EMD Serono                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Deferred revenue                           0     0   $ 800,000  
Up-front, nonrefundable and non-creditable payment received                       $ 10,000,000.0                
Maximum amount eligible to receive for each product developed                                 52,500,000      
Milestone Payment and Supply Agreement | EMD Serono                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Total revenue                           300,000   600,000 2,600,000 2,100,000    
Milestone Payment | EMD Serono                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Total revenue                           1,000,000.0     1,000,000.0      
Supply Agreement | Vaxcyte, Inc.                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Total revenue                           $ 200,000   $ 800,000 $ 300,000 $ 1,100,000    
Research Development and Commercialization Agreement | The Leukemia & Lymphoma Society, Inc.                                        
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                                        
Milestone payment received           1,000,000.0                            
Maximum contribution in clinical development           6,000,000.0                            
Initial milestone payment           500,000                            
Maximum aggregate payment           $ 19,500,000