Quarterly report pursuant to Section 13 or 15(d)

Equity Incentive Plans, Equity Inducement Plans, Employee Stock Purchase Plan and Stock-Based Compensation (Tables)

v3.23.2
Equity Incentive Plans, Equity Inducement Plans, Employee Stock Purchase Plan and Stock-Based Compensation (Tables)
6 Months Ended
Jun. 30, 2023
Share-Based Payment Arrangement [Abstract]  
Summary of Option Activity

The following table summarizes option activity under the Company’s 2004 Plan, 2018 Plan and 2021 Plan:

 

 

 

Shares

 

 

Weighted-
Average
Exercise Price

 

Stock options outstanding at December 31, 2022

 

 

7,310,611

 

 

$

12.68

 

Granted

 

 

1,368,000

 

 

 

5.66

 

Exercised

 

 

(53,060

)

 

 

5.92

 

Canceled and forfeited

 

 

(273,892

)

 

 

11.24

 

Stock options outstanding at June 30, 2023

 

 

8,351,659

 

 

 

11.62

 

Stock options exercisable at June 30, 2023

 

 

5,735,042

 

 

$

12.83

 

Summary of Status and Activity of Non-vested RSUs

A summary of the status and activity of non-vested RSUs during the six months ended June 30, 2023 is as follows:

 

 

 

Number of
shares

 

 

Weighted
Average
Grant-Date
Fair Value

 

Non-vested December 31, 2022

 

 

3,958,478

 

 

$

11.70

 

Granted

 

 

2,305,225

 

 

 

5.80

 

Vested and released

 

 

(896,269

)

 

 

12.52

 

Canceled and forfeited

 

 

(155,260

)

 

 

10.72

 

Non-vested June 30, 2023

 

 

5,212,174

 

 

$

8.98

 

Schedule of Stock-Based Compensation Expense Recognized

Total stock-based compensation expense recognized was as follows:

 

 

 

Three Months Ended

 

 

Six Months Ended

 

 

 

June 30,

 

 

June 30,

 

 

 

2023

 

 

2022

 

 

2023

 

 

2022

 

 

 

(in thousands)

 

 

(in thousands)

 

Research and development expense:

 

$

3,127

 

 

$

2,271

 

 

$

5,948

 

 

$

4,884

 

General and administrative expense:

 

 

3,534

 

 

 

4,425

 

 

 

6,734

 

 

 

8,786

 

Total

 

$

6,661

 

 

$

6,696

 

 

$

12,682

 

 

$

13,670