Annual report pursuant to Section 13 and 15(d)

Income Taxes - Schedule of Effective Tax Rate of Provision (Benefit) for Income Taxes (Details)

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Income Taxes - Schedule of Effective Tax Rate of Provision (Benefit) for Income Taxes (Details)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Income Tax Disclosure [Abstract]      
Federal statutory rate 21.00% 34.00% 34.00%
Change in valuation allowance (32.70%) 20.80% 53.00%
Tax credits 7.50% 3.80% (21.60%)
Stock compensation (0.50%)    
Remeasurement of federal tax rate change   (63.40%)  
Other 4.70% 4.80% (65.40%)
Total 0.00% 0.00% 0.00%